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Dried plums found effective for prevention of BMD loss in osteopenic postmenopausal women
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Investigators of this study found dried plums prevented total body bone mineral density loss in older osteopenic postmenopausal women and that both 50 g and 100 g of dried plum doses were effective in preventing bone loss.
Researchers identified 48 osteopenic postmenopausal women and randomly assigned them to the following treatment groups: 50 g of dried plum; 100 g of dried plum; and 0 g of dry plum. At baseline and 6 months postoperatively, investigators used dual-energy X-ray absorptiometry to evaluate total body, hip and lumbar bone mineral density (BMD), as well as measured osteoprotegerin, receptor activator of nuclear factor kappa-B ligand, calcium, phosphorous and vitamin D. Also, at baseline, 3 months and 6 months, investigators measured bone-specific alkaline phosphatase (BAP), tartrate-resistant acid phosphatase (TRAP-5b), high-sensitivity C- reactive protein, insulin-like growth factor-1 and sclerostin.
Shirin Hooshmand
Findings showed both the 50 g of dried plum and 100 g of dried plum prevented total body BMD loss compared with no dose of dried plum. Investigators noted TRAP-5b had decreased at 3 months in both dosed groups and was sustained at 6 months. There were no differences between the 50 g of dried plum and 100 g of dried plum groups with regard to BAP changes; however, at 6 months, the BAP/TRAP-5b ratio was significantly greater in the two dosed groups compared with the control group that received 0 g of dried plum. ‒ by Monica Jaramillo
Disclosure: Researchers report no relevant financial disclosures.
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