Study indicates Girdlestone aspiration does not accurately detect persistent infection before THA
Results from this retrospective study demonstrated infection persistence could not be reliably confirmed or excluded with the use of Girdlestone aspiration in patients undergoing two-stage revision total hip arthroplasty.
Researchers examined data from 69 patients who were suspected of having periprosthetic joint infection (PJI) and were, therefore, thought to need two-stage revision total hip arthroplasty. Before the explanation procedure, investigators performed an explanation of arthroplasty components used, foreign materials and polymethylmethacrylate cement in order to have a true Girdlestone resection arthroplasty. Investigators took synovial cultures and serum C-reactive protein levels of patients before explantation of the arthroplasty components and of the Girdlestone hip prior to reimplantation. Histological and microbiological samples were also collected.
Findings showed of the 69 patients suspected of a preoperative PJI, 96% had the condition. For synovial aspiration of the Girdlestone hip, the sensitivity was 13% and the specificity was 98%. The sensitivity and specificity for the serum C-reactive protein for Girdlestone hips was 95% and 20%, respectively. ‒ by Monica Jaramillo
Disclosures: Janz reports no relevant financial disclosures. Please see the full study for a list of all other authors’ relevant financial disclosures.