This article is more than 5 years old. Information may no longer be current.
Intra-articular knee injection 3-months prior to TKA linked with higher incidence of infection
Patients who received ipsilateral intra-articular knee injection within 3 months prior to total knee arthroplasty experienced a significantly increased incidence of postoperative infection compared with controls, according to results.
Using the PearlDiver Patient Records Database, researchers identified 35,890 patients who underwent total knee arthroplasty (TKA) after ipsilateral knee injection from 2005 to 2011. Researchers categorized patients into the following cohorts: patients who received TKA within 3 months after ipsilateral knee injection (n=5,313), TKA within 3 months and 6 months after ipsilateral knee injection (n=8,919), and TKA between 6 months and 12 months after ipsilateral knee injection (n=8,008). Finally, researchers created a matched control cohort that underwent TKA without any prior documented knee injection (n=13,650).
Compared with the control group, results showed patients who received ipsilateral knee injection 3 months prior to TKA had a significantly higher incidence of infection within 3 months and 6 months. However, patients who underwent TKA between 3 months and 6 months or 6 months and 12 months after ipsilateral knee injection experienced no significant difference in infection rates vs. the control group, according to the researchers. – by Casey Tingle
Disclosures: Cancienne reports no relevant financial disclosures. Please see the full study for a list of all other authors’ relevant financial disclosures.