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Early results indicate bioresorbable calcium phosphate cement effective for tibial plateau fractures
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PRAGUE — Results of a prospective matched series of patients with Schatzker type VI tibial plateau fractures treated with open reduction and internal fixation showed those who had procedures done with bioresorbable calcium phosphate cement had fewer instances of secondary collapse and experienced similar clinical results compared with cases that had autologous bone grafting.
“Regarding union rate, recovery, clinical results and complications, the use of bioresorbable calcium [phosphate] cement does not provide better results than conventional augmentation, but radiological results are better for the rCPC [bioresorbable calcium phosphate cement] group,” Alexandre Lunebourg, MD, of the Hôpital Sainte Marguerite in Marseille, France, said during his presentation at the 16th EFORT Congress. “Studies with longer follow-up are needed to confirm this good earlier result, especially regarding the development of osteoarthritis.”
Lunebourg and colleagues studied 20 patients in each group who were matched for age and sex. Overall, most of the patients in the study were men. Patients had a mean age of 41 years and a mean BMI of 24. The patients were evaluated at 3 months, 6 months and annually after fixation. Mean follow-up was 16 months.
Alexandre Lunebourg
The researchers found no significant difference between the groups regarding the rate of union, and Lunebourg noted the time to union in both groups was about 5 months. The study also showed no significant difference regarding recovery between the groups, with most patients returning to work at about 8 months and returning to sports at about 9 months. Additionally, the researchers did not observe any significant difference between the groups regarding KOOS scores.
“Regarding the radiological results, we observed that secondary loss of reduction was significantly greater in the control group than in the rCPC group at the last follow-up,” Lunebourg said.
He said the study was limited by its nonrandomized design, presentation of some patients with associated lesions and the use of various fixation combinations, such as plate-and-screw, two plates or screw only fixation. – by Gina Brockenbrough, MA
Reference:
Lunebourg A, et al. Paper #2391. Presented at: 16th EFORT Congress; May 27-29 2015; Prague.
Disclosure: Lunebourg reports no relevant financial disclosure.