This article is more than 5 years old. Information may no longer be current.
High union rate, tumor society scores seen with frozen autograft-prosthesis composite reconstruction
Click Here to Manage Email Alerts
Investigators found a union rate of 90% and an average Musculoskeletal Tumor Society score of 89.3% in a minimum 2-year follow-up of patients with sarcoma or cancer who were treated with frozen autograft-prosthesis composite reconstruction.
Researchers retrospectively reviewed information for 19 patients with bone sarcoma and three patients with bone metastasis who underwent tumor excision and reconstruction using frozen autograft-prosthesis composites. Patients had a minimum 2-year follow-up, and mean follow-up was 65 months.
Radiograph or CT was used to confirm evidence of graft union. Investigators noted time to union and determined graft survival using the Kaplan-Meier method. They also noted Musculoskeletal Tumor Society scores and complications.
Half of the patients underwent reconstruction using a pedicle-freezing method, and half were reconstructed using the free-freezing method. The average bone length was 16 cm, and the average graft time to union was 9.5 months.
Complications developed in seven patients. Three patients developed soft tissue tumor recurrence, two patients had graft infections and two had graft fractures. Two grafts were considered dead due to hip disarticulation from soft tissue recurrence and were revised to a tumor prosthesis.
“The survival rate for the frozen autografts was 94% over 5 [years] and 10 years,” the researchers wrote. ‒ by Monica Jaramillo
Disclosures: The researchers report no relevant financial disclosures.
Click Here to Manage Email Alerts