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TKA likely safe, useful in patients with a history of solid organ transplant
Although patients with a history of solid organ transplant who underwent total knee arthroplasty experienced increased — with relatively modest clinically significant — length of stays, costs and complications, investigators of this study noted the safety and efficacy of arthroplasty for these patients.
Researchers identified 6,104 patients with a history of solid organ transplant who underwent primary total knee arthroplasty (TKA) and compared them with 5,864,317 non-transplant total knee arthroplasty patients.
Compared with non-transplant patients, investigators found a significantly higher prevalence of hypertension, diabetes, rheumatoid arthritis and drug abuse among patients with a history of solid organ transplantation. However, patients with a history of solid organ transplant had a significantly lower prevalence of obesity, hypothyroidism and chronic pulmonary disease.
Researchers found a higher mean overall length of stay, as well as a higher overall unadjusted mean total cost per admission, among transplant plants. Statistically significant differences in infection and the need for a transfusion of blood products were found between the patient groups, showing higher complications of both occurrences in transplant patients.
After propensity score adjustment, researchers found a 0.44-day longer length of stay and a $962 higher cost of admission among transplant patients. According to results, patients with a history of transplantation also were associated with a 1.43-times higher odds of any complication. – by Casey Tingle
Disclosures: Klika reports no relevant financial disclosures. Please see the full study for a list of all other authors’ relevant financial disclosures.