August 09, 2015
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Osteochondral allograft transplantation improved functional scores, survivorship

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Osteochondral allograft transplantation performed as either primary treatment or after failure of previous subchondral marrow stimulation had favorable results, with significant improvement of functional scores and excellent survivorship, according to study results.

Researchers identified 46 knees that underwent osteochondral allograft (OCA) transplantation as primary treatment (group one) and 46 knees that underwent OCA transplantation after failure of previous subchondral marrow stimulation (group two). Modified Merle D’Aubigné-Postel scale, IKDC subjective knee evaluation form, KOOS and Knee Society function (KS-F) scale were evaluated for functional outcomes. The researchers also recorded patient satisfaction up to the latest follow-up.

William D. Bugbee

 

Results showed 24% of knees in group one underwent reoperation vs. 44% of knees in group two. The researchers also found 11% of knees in group one and 15% of knees in group two had OCA classified as a failure. Survivorship of the graft was 87.4% in group 1 and 86% in group 2 at 10 years follow-up, according to study results.

From preoperatively to the latest follow-up, the researchers found improvements in pain and function in both groups on all subjective scores. Overall, 87% of patients in group one and 97% of patients in group two were satisfied or extremely satisfied with OCA transplantation, according to the researchers. – by Casey Tingle

Disclosures: Gracitelli reports receiving support from Coordination for the Improvement of Higher Education Personnel of Brazil. Please see the full study for a list of all other authors’ relevant financial disclosures.