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Treatment after TKA may help control infection and maintain functional TKA
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Except among patients with late chronic methicillin-resistant Staphylococcus aureus or methicillin-resistant Staphylococcus epidermidis, treatment for infection after total knee arthroplasty controlled infection and maintained functional total knee arthroplasty in most patients, according to study results.
Researchers reviewed 50 patients with deep infection with or without a resistant organism at the site of total knee arthroplasty (TKA). Treatment with debridement, antibiotic therapy and retention of the prosthesis with revision of the polyethylene insert was performed among 13 patients with early deep infection and four patients with acute hemotogenous infections, whereas 33 patients with late chronic infections underwent either challenging prosthesis retention for prostheses that had not loosened or two-stage exchange arthroplasty for prostheses that had loosened.
Tomoyuki Matsumoto
For resultant functional knees and mean number of operations, no significant differences were observed between seven patients with resistant early deep infections and six patients with nonresistant early deep infections, according to study results. However, the researchers found significant improvements in resultant functional knees and fewer mean operations in 24 patients with nonresistant chronic infections vs. nine patients with resistant chronic infections.
Results also showed 89% of patients with resistant chronic infections had either arthrodesis or underwent above-the-knee amputation or spacer arthroplasty. – by Casey Tingle
Disclosure: The researchers report no relevant financial disclosures.
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