March 11, 2015
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Artificial disc replacement offers no improvement over fusion in neck pain scores

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Neck Disability Index scores showed artificial disc replacement did not produce better outcomes compared with fusion, according to researchers.

One hundred fifty-three patients seeking treatment for cervical radiculopathy who fulfilled the researchers’ inclusion criteria were included in the randomized, controlled, multicenter study. Patients were randomly assigned to treatment with the Depuy Discover artificial disc (ADR) or fusion with iliac crest bone graft and plating (ACDF). The researchers recorded data on adverse events, complications, revision surgery and loss to follow-up. Two-year follow-up data were available for 137 patients.

The researchers found both treatment groups improved significantly after surgery, but no statistically significant differences were found in Neck Disability Index scores at follow-up between the two groups (39.1 vs. 40.1).

Additionally, no statistically significant differences were observed in secondary outcome measures, such as VAS and EQ-5D scores, and complication rates were similar between the two groups, as well, according to the researchers. – by Robert Linnehan

Disclosure: Skeppholm has received grants from DePuy Spine Sweden, Stockholms Läns Landstring, the Swedish Society for Spine Surgery; support for travel to meetings for the study or other purposes from DePuy Spine Sweden; and speaking and/or teaching arrangements from DePuy Spine Sweden. Please see the full study for a list of all other authors’ relevant financial disclosures.