October 17, 2014
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Smoking associated with higher perioperative risks after cervical corpectomy

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Patients who smoked were found to have higher rates of perioperative complications, longer lengths of hospital stay and higher rates of pseudarthrosis after undergoing anterior cervical corpectomy, according to researchers.

One hundred sixty adult patients who underwent anterior cervical corpectomy from 2006 to 2011 were included in the study. Among the patients, 79 were nonsmokers, 41 were quitters and 40 were current smokers.

The researchers collected demographic, medical and surgical covariates and used multivariate analysis to define the relationship between smoking status and blood loss, 30-day complication rates, length of hospital stay and occurrence of pseudarthrosis.

Overall 30-day complication rate was 20%, and the researchers found pseudarthrosis occurred in 7.6% of the patients. Additionally, mean blood loss was 368.3 mL, and mean length of hospital stay was 6.5 days.

Current smoking status was found to be significantly associated with higher complication rates and longer hospital stays, according to the researchers. After multivariate logistic regression analysis, current smoking status remained an independent risk factor for both outcomes.

Patients who were current smokers experienced a significantly higher occurrence of complications, including infections, than nonsmokers and quitters, according to the researchers.

The researchers found current smoking status was also independently associated with a risk for pseudarthrosis at the 1-year follow-up.

Disclosures: Mummaneni has received royalties from DePuy Spine, Quality Medical Publishers, and Thieme Publishers; honoraria from Globus and Depuy Spine; and has purchased stock in Spinicity. Chou has received honoraria from Globus, Medtronic, Depuy and Orthofix for teaching.