October 01, 2014
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Girls have higher incidence, risk of osteochondritis dissecans than boys

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Compared with male patients, female patients had a greater incidence of osteochondritis dissecans and a 1.5-times greater risk for ankle osteochondritis dissecans, according to study results.

Researchers performed a retrospective chart review of an integrated health system from 2007 to 2011 for patients between the ages of 2 and 19 years with ankle osteochondritis dissecans (OCD), recording lesion location, laterality and all patient demographics. The researchers determined ankle OCD for the group as a whole and by both sex and age group and assessed the risk for ankle OCD for age group, sex and ethnicity using multivariate logistic regression models.

Overall, 85 patients fit inclusion criteria. Although the researchers found no ankle OCD lesions in 2- to 5-year-olds, the incidence of ankle OCD in patients between 6 and 19 years was 4.6 per 100,000.

For male patients, overall incidence of ankle OCD was 3.2 per 100,000 compared with 6 per 100,000 for female patients, according to study results. The vast majority of patients with OCD were between 12 and 19 years old, with an incidence of 6.8 per 100,000 compared with 1.1 per 100,000 in patients 6 to 11 years of age.

Study results showed an incidence of 1.5 per 100,000 in female patients between the ages of 6 and 11 years vs. 8.9 per 100,000 in female patients 12 to 19 years. In comparison, male patients between the ages of 6 and 11 years had an incidence of 0.7 per 100,000 vs. 4.8 per 100,000 in male patients between the ages of 12 and 19 years, according to the researchers.

According to the results of the multivariate logistic regression analysis, patients between the ages of 12 and 19 years had a 6.9-times increased risk for ankle OCD compared with patients 6 to 11 years of age. The researchers also found a 1.5-times greater risk for ankle OCD among female patients vs. male patients.

Disclosure: The authors have no relevant financial disclosures.