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Osteoporosis frailty index may predict health risks in women
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The frailty index was a predictor of falls, fractures, overnight hospitalization and death in women with osteoporosis, according to study results.
Researchers culled data on 3,985 women older than 55 years enrolled in the Hamilton Cohort of the Global Longitudinal Study of Osteoporosis in Women (GLOW) between May 2008 and March 2009. Utilizing 34 health deficits at baseline, the researchers’ frailty index (FI) consisted of patient co-morbidities, activities of daily living, symptoms and signs and health care utilization.
According to the researchers, the FI was significantly associated with age, and a mean rate of deficit accumulation across baseline age of 0.004 or 0.021 annually was observed. A total of 1,068 women reported a minimum of one fall at 3-year follow-up, the risk of which increased substantially for every 0.01 on the FI.
FI was also significantly associated with risk of fracture, overnight hospitalization and death. With each increment in the FI, odds ratios were 1.21 for falls and 1.40 for death, hazard ratio was 1.17 for fracture and the instance rate ratio was 1.18 for overnight hospitalization, according to the researchers.
Disclosure: The authors have no relevant financial disclosures.
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