July 25, 2014
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Study determines utility values for patients with certain health states

In a recent study, researchers assigned the first-ever calculated health state utility values for single-level cervical degenerative disc disease, anterior cervical discectomy and fusion, or cervical disc replacement.

Sheeraz Qureshi, MD, MBA, and colleagues analyzed the results of the SF-36 Health Survey, which was administered to patients with single-level cervical degenerative disc disease at baseline, and at 24 months after anterior cervical discectomy and fusion (ACDF) or cervical disc replacement (CDR), during the ProDisc-C investigational device exemption study.

Using the SF-6, the researchers calculated utility scores for each health state based on a set of parametric preference weights obtained from a sample of the general population through the valuation technique of standard gamble.

Qureshi and colleagues calculated the health state utility value for a patient with single-level degenerative disc disease to be 0.54 at baseline in both the ACDF and CDR groups. At 24-month follow-up, CDR had a health state utility value of 0.72, and ACDF had a health state utility value of 0.71. This difference was not considered statistically significant; however, both treatment interventions were considered to significantly impact health state utility values, according to the researchers.

“This study, based on outcomes from a multicenter, randomized, controlled trial of the ProDisc-C prosthesis, has assigned [health state utility] values to the preoperative single-level cervical [degenerative disc disease] state, as well as the postoperative states for CDR and ACDF,” Qureshi and colleagues wrote in the study. “This is the first study to assign these values. Health state utility values are integral in future [cost-effectiveness analyses] of the two procedures. According to our data, both procedures are equally effective in the treatment of single-level cervical DDD.”

Disclosure: Qureshi is a consultant for Stryker, Medtronic and Orthofix.