July 09, 2014
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Abnormal pedicles more prevalent in patients with adolescent idiopathic scoliosis

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Recent study data have shown patients with adolescent idiopathic scoliosis tend to have a higher prevalence of abnormal pedicles than patients without spinal deformity.

Researchers analyzed CT images of 6,116 pedicles from 95 patients without spinal deformities and 91 patients with adolescent idiopathic scoliosis (AIS). Pedicles with a cancellous channel of 2 mm to 4 mm, a cortical channel of 2 mm or greater, or a cortical or cancellous channel of less than 2 mm were considered abnormal. The researchers assessed patient demographic data and pedicle distribution to determine the prevalence and likelihood of abnormal pedicle morphology.

Patients with AIS were found to have a significantly higher rate of abnormal pedicles; 665 of 3,094 pedicles were found to be abnormal in patients with AIS, compared with 295 of 3,022 pedicles found to be abnormal in patients without any deformity.

The researchers found significantly more abnormal pedicles located on the thoracic spine than on the lumbar spine in both patient groups. Additionally, more abnormal pedicles were found on the concavity within the periapical region and on the apex curve.

Pedicle screws were three times more likely to be misplaced in abnormal pedicles than in normal pedicles, according to the researchers.

Disclosure: The authors have no relevant financial disclosures.