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Patients more likely to develop adjacent segment disease above index ACDF, study shows
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The highest rate of cervical degenerative disease needing additional surgery after anterior cervical discectomy and fusion were in levels C5/C6 and C6/C7 in patients with cervical spondylosis, according to a recently published data.
“Interestingly, neither the inherent location of index [anterior cervical discectomy and fusion] ACDF nor the length of instrumented arthrodesis affected the propensity to develop [adjacent segment disease] ASD,” Mohamad Bydon, MD, and colleagues from Johns Hopkins University School of Medicine, wrote in the study.
Bydon and colleagues analyzed 108 patients who underwent repeat ACDF for the treatment of cervical spondylosis at a single center during a 20-year period, according to the abstract. Patients were followed until mean 92.4 months after the first surgery.
“Patients were statistically more likely to develop ASD above—compared to below—the index level of fusion. This was true even for patients undergoing a second revision surgery due to recurrent ASD,” Byron and colleagues wrote. — by Jeff Craven
Disclosure: Bydon received a grant from DePuy Spine and is on the clinical advisory board of Medimmune
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