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Study: PRP does not significantly improve quality of life, outcome for patients with rotator cuff tendinopathy
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Patients who were treated with platelet-rich plasma for chronic rotator cuff tendinopathy did not have significantly improved quality of life pain, disability and shoulder range of motion when compared to patients who underwent an exercise program alone, according to results of this study.
“At 1-year follow-up, a [platelet-rich plasma] PRP injection was found to be no more effective in improving quality of life, pain, disability, and shoulder range of motion than placebo in patients with chronic [rotator cuff tendinopathy] RCT who were treated with an exercise program,” Serdar Kesikburun, MD, and colleagues wrote in the abstract.
The researchers enrolled 40 patients in a double-blind randomized controlled trial who had a history of shoulder pain for more than 3 months after overhead throwing activities and confirmed a rotator cuff tendinopathy or partial tendon rupture through MRI, according to the abstract. The 5-mL PRP injection or saline solution was put in the subacromial space. All patients then underwent a 6-week exercise program.
At 1-year follow-up, there were no significant differences in Western Ontario Rotator Cuff Index, Shoulder Pain and Disability Index, or VAS scores at any time points, according to the study. There was also no significant difference in shoulder range of motion during any time period.
Disclosure: The authors have no relevant financial disclosures.
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