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Researchers identify factors for poor outcomes after mosaicplasty
Gender, age and lesion size are factors that can influence the long-term success of mosaicplasty, according to this study.
“At long-term (10–14 years) following mosaicplasty, 40% have a poor outcome or fail. Of the remainder, outcome scores are improved compared to preoperation,” Eirik J Solheim, MD, PhD, and colleagues from Norway wrote in their study. “The outcome varies greatly in subgroups of patients with different age, gender and size of the cartilage defect.”
Solheim and colleagues analyzed the Lysholm and VAS scores for 73 patients with symptomatic focal full-thickness chondral lesions who had a median age of 34 years. At both medium follow-up and long-term follow-up, the mean Lysholm and VAS scores significantly improved.
However, at long-term follow-up, 40% of patients had a poor outcome, which investigators characterized as the need for a total knee replacement or having a Lysholm score of 64 points or lower. Patients who had a poor outcome tended to be women, have a lesion size of at least 3 cm2, or were at least 40 years of age, according to the study abstract.
The researchers also analyzed a subgroup of male patients who were younger than 40 years and had a defect size of 4 cm2 or smaller. In these patients, Solheim and colleagues found a mean Lysholm score of 82 and a failure rate of 12.5%, according to the abstract.
Disclosure: The authors have no relevant financial disclosures.