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Bisphosphonate compliance linked to decreased risk of secondary fracture
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After one hip fracture, compliant users of bisphosphonates are less likely to undergo a second hip fracture than nonusers, according to results of this study.
“Bisphosphonate has been used to prevent osteoporotic fracture and is recommended for the secondary prevention after hip fracture,” the researchers wrote in the study abstract. “However, little is known regarding secondary prevention after first hip fracture.”
The researchers retrospectively examined 826 patients who had a hip fracture between 2003 and 2011. Patients were divided into two groups based on bisphosphonate use. At mean 30 months after the initial fracture, 8.6% of patients in the study had a secondary fracture. Of these patients, researchers determined secondary fractures occurred in 4.2% of compliant bisphosphonate users and 10.9% of patients in the control group, according to the abstract.
Overall, the researchers found the cumulative incidence of a secondary fracture 2 years after the initial fracture was 5.1%, and 8 years after the initial fracture was 8.6%.
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