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Low bone mineral density, BMI, intradiscal cement leakage may predict vertebral compression fracture
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Researchers in this study identified low bone mineral density, low body mass index and intradiscal cement leakage as risk factors for an osteoporotic vertebral compression fracture after vertebroplasty.
“The results of this meta-analysis strongly suggested that patients with low [bone mineral density] BMD, low [body mass index] BMI, and intradiscal cement leakage were at high risk for new [vertebral compression fractures] VCFs after vertebroplasty, and risk-reduction options should be considered for such patients,” Zitao Zhang, PhD, and colleagues wrote in the abstract.
Zhang and colleagues identified 16 articles from PubMed comprising 559 cases and 1,736 control patients. The significant risk factors outlined in the meta-analysis were for VCFs adjacent to the treated VCF.
The researchers also evaluated cement volume, age, gender, surgical approach, thoracolumbar junction fractures; in addition to low BMD, low BMI and intradiscal cement leakage, none of the risk factors examined were significant for predicting new VCF away from the original treated fracture site, according to the abstract.
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