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Patients with knee osteoarthritis show higher knee adduction moment at baseline
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PHILADELPHIA — Patients with moderate knee osteoarthritis who have total knee arthroplasty have major differences in gait patterns at baseline that may predict progression of knee osteoarthritis, according to a presenter at the Osteoarthritis Research Society International World Congress.
“There were differences in the pattern of gait in the group that progressed to TKA versus the group who did not,” Gillian Hatfield, MS, BS, of Dalhousie University in Halifax, Nova Scotia, Canada, said, here. “The TKA group had a higher overall magnitude in the knee adduction moment.”
The researchers assessed 50 patients with moderate knee osteoarthritis at baseline and 8 years. Patients underwent gait analysis of ground reaction forces and segment motions. They measured three-dimensional knee angles and moments with inverse dynamics. They used Principal Component Analysis to measure amplitude and temporal waveform characteristics. At 8-year follow-up, the researchers conducted phone interviews with patients and found that 25 patients had undergone total knee arthroplasty (TKA). They then used unpaired Student’s t-tests to find differences in demographics and waveform characteristics between patients who underwent TKA and patients who did not have TKA.
Gillian Hatfield
The investigators found no differences between groups in age, mass, gait speed or disease severity at baseline. The TKA group had a higher knee adduction moment, higher tibial external rotation midstance, reduced early stance knee flexion and late stance knee extension moments than the non-TKA group at baseline.
“Together, these findings indicate that dynamic frontal, transverse and saggital plane mechanical features are related to knee osteoarthritis progression and should be considered in future prediction models of progression,” the authors wrote in the abstract.
Reference:
Hatfield G. Paper #30. Presented at: Osteoarthritis Research Society International World Congress; April 18-21, 2013; Philadelphia.
Disclosure: Orthopedics Today was unable to confirm disclosures at press time.