Issue: February 2013
January 04, 2013
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Researchers find increased fracture risk in adults with diabetes

Issue: February 2013
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Adults diagnosed with diabetes are at a higher risk for fracture resulting in hospitalization, according to recent results from the Atherosclerosis Risk in Communities Study.

“Our results suggest that persons with diagnosed diabetes are at an increased risk for overall fracture-related hospitalization,” Andrea L.C. Schneider, PhD, and colleagues wrote in the study.

“[It] support[s] recommendations from the American Diabetes Association for assessment of fracture risk and implementation of primary and secondary prevention strategies in appropriate patient populations,” the researchers wrote.

Schneider and colleagues found 1,078 fracture-related hospitalizations for the 15,140 study participants at 20-year follow-up, minimum, according to the abstract. They noted an increased adjusted hazard ratio (HR) of 1.74 (95% CI, 1.42-2.14) for increased fracture risk in subjects diagnosed with diabetes. Individuals with diabetes treated with insulin had a 1.87 HR for fracture and subjects with diabetes and glycated hemoglobin levels greater than or equal to 8% had an increased fracture risk vs. individuals with glycated hemoglobin levels less than 8%.

The study subjects not diagnosed with diabetes had no significant risk for fracture resulting in hospitalization compared to other subjects, Schneider and colleagues noted.

Disclosure: The authors received grants from the National Institutes of Health to conduct this study.