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Cortical, trabecular BMD contributes to hip fracture risk in elderly men
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Cortical and trabecular bone are both risk factors for proximal femur fractures in elderly men, according to this study.
In 250 men who were 65 years or older, researchers used quantitative CT scans and calculated cortical, trabecular and integral volumetric bone mineral density (vBMD) and cortical thickness along the trochanter, intertrochanter and femoral neck. Forty of the 250 cases were first hip fractures at mean 5.5 years follow-up, according to the abstract.
Trabecular vBMD was significantly associated with hip fracture at the femoral neck, trochanter and total hip after adjusting for total hip areal BMD. Quantitative CT scans alone or in combination were not significantly better at predicting hip fracture than total hip areal BMD, according to the abstract. After combining total hip areal BMD, age and trabecular BMD in a regression model, the model predicted hip fracture better than total hip areal BMD with age or alone.
“These findings confirm that both cortical and trabecular bone contribute to hip fracture risk and highlight trabecular vBMD at the femoral neck and trochanter as an independent risk factor,” the researchers stated in the study abstract.
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