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Hyaluronic acid effective for treatment of early-stage ankle OA

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Tae hun Kim

A 1-year follow-up shows that intra-articular hyaluronic acid injection may provide a high rate of satisfaction for patients with early stage ankle osteoarthritis, according to a study presented at the 2011 Annual Meeting of the American Orthopaedic Foot and Ankle Society.

“Hyaluronic acid injection is an efficient and durable treatment method for early stage ankle osteoarthritis,” study researcher Tae hun Kim, MD, said during his presentation.

For the study, patients with early-stage ankle osteoarthritis (OA) who had unsuccessful treatment with 3 months of oral medical therapy received intra-articular hyaluronic acid injection. The study included 27 patients, 13 men and 14 women, with a mean age of 58 years. They received injections of 2 mL of high-molecular weight hyaluronic acid for 3 weeks each.

The investigators measured the outcomes of the treatment using the Visual Analog Scale (VAS), patient satisfaction score and Takakura stage. They followed-up with patients after the procedure and at 3 months and 6 months, and followed 20 patients for up to 1 year. Average follow-up duration was 16 months.

Investigators categorized eight patients as Takakura Stage I and 12 patients were Takakura Stage II. Before injection, the VAS score was 8.8 ± 0.7. At 3-month follow-up, the average VAS score was 36 ± 0.2. Patient satisfaction score was 90%. Investigators found that eight patients reported themselves as very satisfied with the procedure, seven people were satisfied, three rated it as fair and two were not satisfied. There were no postoperative radiologic OA stage changes.

Reference:

• Kim TH, Han SH, Jo J. One-year follow-up efficacy of intra-articular hyaluronic acid injection in early stage ankle OA. Paper #084. Presented at the 2011 Meeting of the American Orthopaedic Foot and Ankle Society. July 13-16. Keystone, Colo.
• Disclosure: Kim has no relevant financial disclosures.

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