Cornea Central

• Neurotrophic keratitis affects approximately 6% of herpetic keratitis cases, 12.8% of herpes zoster keratitis cases and 2.8% of patients who had a surgical procedure for trigeminal neuralgia.
• Early diagnosis of neurotrophic keratitis with basic corneal sensitivity testing can profoundly affect patient outcomes.
• Complications of keratitis include chronic corneal inflammation and scarring, chronic or recurrent viral infections of the cornea, corneal ulcers, temporary reduction in vision and blindness.
• Approximately 30,000 Americans lose their sight each year because of uveitis.
• People with Fuchs’ dystrophy usually become symptomatic at 50 to 60 years.
• Iridocorneal endothelial syndrome is most common in women aged 30 to 50 years.
• As of now, there is no cure for herpetic eye disease, although various treatments can help prevent vision loss.
• An estimated 30% of patients with transplanted corneas experience at least one episode of immune rejection. In high-risk corneal transplant cases, 70% fail within 10 years.

References:

• Cleveland Clinic. Herpetic Eye Disease. https://my.clevelandclinic.org/health/diseases/8861-herpetic-eye-disease. Accessed Feb. 15, 2023.
• Cleveland Clinic. Keratitis. https://my.clevelandclinic.org/health/diseases/24500-keratitis. Accessed Feb. 15, 2023.
• Cleveland Clinic. Uveitis. https://my.clevelandclinic.org/health/diseases/14414-uveitis. Accessed Feb. 15, 2023.
• Mayo Clinic. Keratitis. https://www.mayoclinic.org/diseases-conditions/keratitis/symptoms-causes/syc-20374110?p=1. Accessed Feb. 15, 2023.
• National Eye Institute. Corneal Conditions. https://www.nei.nih.gov/learn-about-eye-health/eye-conditions-and-diseases/corneal-conditions. Accessed Feb. 15, 2023.
• National Eye Institute. Corneal Dystrophies. https://www.nei.nih.gov/learn-about-eye-health/eye-conditions-and-diseases/corneal-conditions/corneal-dystrophies. Accessed Feb. 15, 2023.
• National Library of Medicine. Neurotrophic Keratitis. https://www.ncbi.nlm.nih.gov/books/NBK431106/. Accessed Feb. 15, 2023.
• The College of Optometrists. Corneal Transplant Rejection. https://www.college-optometrists.org/clinical-guidance/clinical-management-guidelines/cornealtransplantrejection. Accessed Feb. 15, 2023.