Fact checked byHeather Biele

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May 08, 2023
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Several factors affect VA outcomes after cataract surgery in patients with type 2 diabetes

Fact checked byHeather Biele
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Key takeaways:

  • Two-thirds of patients with diabetes achieved a visual outcome of 20/40 or better after cataract surgery.
  • Preoperative visual acuity and diabetic retinopathy were associated with visual outcomes.
Perspective from Saidivya Komma, OD, FAAO

Although visual prognosis after cataract surgery is usually favorable, factors such as diabetic retinopathy may still limit visual potential in those with type 2 diabetes, according to a study published in the British Journal of Ophthalmology.

“This is one of the largest studies to assess VA outcomes in people with diabetes undergoing cataract surgery,” Debora Lee, from the division of epidemiology and clinical applications at the National Eye Institute, and colleagues wrote. “Furthermore, this study provides an updated benchmark of the prevalence of good visual outcome after cataract surgery in a contemporary population with diabetes.”

Cataract eye 1

Cataract surgery outcomes were influenced more by ocular parameters than systemic. Image: Adobe Stock

Researchers from the National Eye Institute and Wake Forest University conducted a retrospective case-control study of patients with type 2 diabetes enrolled in the multicenter, randomized Action to Control Cardiovascular Risk in Diabetes (ACCORD) study and ACCORD-eye substudy. They evaluated 1,136 eyes of 784 participants (mean age, 65.6 years; 58.4% men) who underwent cataract surgery from 2001 to 2014.

Of a subsample of 362 eyes from 251 patients who received fundus photographs gradable for diabetic retinopathy, 49.4% had no diabetic retinopathy, 13.8% had mild non-proliferative diabetic retinopathy (NPDR), 34.3% had moderate NPDR, 0.8% had severe NPDR, and 1.7% had proliferative diabetic retinopathy.

According to results, 762 eyes (67.1%) achieved a good visual outcome of at least 20/40, and among the subset that underwent fundus photographs, 265 eyes (73.2%) achieved a good outcome.

Significant predictors of good visual outcome included high level of education (OR = 2.35), bilateral cataract surgery (OR = 1.55) and preoperative visual acuity (OR = 10.59). In the subsample of 362 eyes, the presence or absence of diabetic retinopathy also influenced visual outcomes (OR = 1.73).

Factors that were not significantly associated with visual outcome included age, sex, race, smoking, diabetes duration, blood pressure, lipid levels and HbA1C.

“Notable factors associated with visual outcomes included preoperative VA and diabetic retinopathy, but not HbA1C, underscoring that while certain ocular measures may help to evaluate visual potential, systemic parameters may not be as valuable. Socioeconomic status and related issues may also be important considerations,” Lee and colleagues wrote.