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February 21, 2024
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En face OCT identifies cRORA as hypertransmission defects

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Analyzing en face OCT images for hypertransmission defects can quickly identify complete retinal pigment epithelium and outer retinal atrophy, according to a presentation at Angiogenesis, Exudation, and Degeneration 2024.

Omer Trivizki, MD, MBA, and colleagues compared the gradings of complete retinal pigment epithelium and outer retinal atrophy (cRORA) and incomplete retinal pigment epithelium and outer retinal atrophy (iRORA) on OCT B-scans with hypertransmission defects (hyperTDs) on en face images.

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Analyzing en face OCT images for hypertransmission defects can quickly identify complete retinal pigment epithelium and outer retinal atrophy, according to a presentation at Angiogenesis, Exudation, and Degeneration 2024.

Nearly all instances of cRORA overlapped with persistent hyperTDs when the image types were compared. Additionally, about half of the cases of iRORA were already in hyperTD and could be cRORA if they were measured differently.

Trivizki said the grading exercise shows that grading of en face images is more accurate, faster, easier and likely more reproducible. Because it takes only a few seconds, inspecting a single en face image can be done more quickly than evaluating all B-scans, Trivizki said.

“En face imaging is a powerful method to identify cRORA as persistent hypertransmission defects,” he said. “When an iRORA lesion is suspected, neighboring closely spaced B-scans should be inspected.”