Retinal Pigment Epithelium

The color of a blue iris is not produced by so-called pigment coloring — the simple form of selective color absorption that produces the hue of everyday objects like blueberries or blue jeans.

PARK CITY, Utah — In this Healio Video Perspective from Clinical Trials at the Summit, Lori Taylor of Annexon Biosciences previews data on ANX007 for the treatment of geographic atrophy.

SEATTLE — In this video, Eleonora M. Lad, MD, PhD, vice chair of ophthalmology clinical research at Duke Health, discusses a presentation at the ARVO meeting on retinal pigment epithelium cells in age-related macular degeneration.

Analyzing en face OCT images for hypertransmission defects can quickly identify complete retinal pigment epithelium and outer retinal atrophy, according to a presentation at Angiogenesis, Exudation, and Degeneration 2024.

SEATTLE — Based on the amount of retinal tissue preserved, pegcetacoplan saves 5,000 to 9,000 retinal pigment epithelium cells over a period of 2.5 years and up to 15,000 in extrafoveal lesions, according to a study presented here.

Interim results from a study investigating OpRegen suggest a single treatment may provide improvements in patients with dry age-related macular degeneration with geographic atrophy, according to a Lineage Cell Therapeutics press release.

A post hoc analysis of the phase 2 FILLY study demonstrated that patients who received multiple intravitreal injections of pegcetacoplan had a lower rate of progression from nascent geographic atrophy to GA as compared with sham.

A 61-year-old man presented to the Lahey Clinic Emergency Department with a 4-day history of sudden onset painless blurred vision in the right eye. More specifically, he described a new “blind spot” just temporal to central vision.

Why doesn’t our superior retina detach? Why does it stay pressed against the retinal pigment epithelium? It would stand to reason that — especially once we’ve had a vitreous detachment — gravity would just let it slip off every now and then.

In patients treated with hydroxychloroquine, multifocal electroretinography could detect abnormalities in macular function early, before overt maculopathy was present, according to a study.