Study provides update on NAION risk factors, prevalence in US
Click Here to Manage Email Alerts
Key takeaways:
- NAION is notably present in white men and Black men and women.
- NAION is significantly associated with diabetes, hyperlipidemia, obstructive sleep apnea and phosphodiesterase inhibitor use.
A study investigating nonarteritic ischemic optic neuropathy in the U.S. found notable prevalence in white men and Black men and women and frequent association with diabetes and high cholesterol levels.
The study, presented in a poster at the North American Neuro-Ophthalmology Society meeting by Sari Yordi, MD, and co-authors, investigated the prevalence of nonarteritic ischemic optic neuropathy (NAION) in the United States between 2015 and 2021 using TriNetX, a cross-sectional database with more than 85 million deidentified patient encounters. A total of 20,821 patients (43 per 100,000) with NAION were identified.
Image: Adobe Stock
A significant association was found with diabetes, hyperlipidemia, obstructive sleep apnea and the use of phosphodiesterase inhibitors. Stratification by race and ethnicity showed the highest proportion of cases among white men (37 per 100,000), Black men (31 per 100,000) and Black women (31 per 100,000).
NAION is one of the most common causes of optic neuropathy in adults, the authors noted, but data on prevalence are lacking and provide conflicting information. This study was able to give an updated view of the current situation in the U.S.
“Future studies are needed to better understand the real-world incidence of this vision-threatening disease,” the authors said.
Collapse
Yordi S, et al. Updated prevalence of non-arteritic ischemic optic neuropathy in the United States and its association with known systemic risk factors. Presented at: North American Neuro-Ophthalmology Society meeting; March 11-16, 2023; Orlando, Florida.
Read more about
Click Here to Manage Email Alerts