PreserFlo microshunt leads to minimal transient anterior segment changes
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Key takeaways:
- Minimally invasive glaucoma surgery with the PreserFlo microshunt leads to good IOP control.
- Matteo Carlà, MD, discussed study results evaluating anterior segment changes after PreserFlo implantation.
VILAMOURA, Portugal — Minimally invasive glaucoma surgery with the PreserFlo microshunt leads to good IOP control with minimal anterior segment parameter variations, according to a study presented here.
“The purpose of our study was to evaluate anterior segment changes induced by PreserFlo implantation in the early postoperative period,” Matteo Carlà, MD, said at the European Society of Cataract and Refractive Surgeons winter meeting. “We included 48 eyes with uncontrolled primary open-angle glaucoma on maximum tolerated medications, both phakic and pseudophakic.”
PreserFlo surgery (Santen) was performed as a stand-alone procedure or in combination with cataract surgery. Anterior chamber depth (ACD), anterior chamber volume (ACV), central corneal thickness (CCT) and total corneal astigmatism (TCA) were evaluated preoperatively and postoperatively at day 1 and day 7 with Pentacam tomography (Oculus).
Mean IOP was 21 mm Hg before surgery, 8 mm Hg at day 1 and 10 mm Hg at day 7. Hypotony occurred in one case at day 1, self-limiting at day 7, and mild hyphema occurred in eight eyes, fully resolved at day 7.
Pentacam analysis showed an increase in TCA at day 1, due to alterations in one of the axes of corneal curvature, and an increase in CCT at day 1, returning to preoperative values at 1 week. Both ACD and ACV showed only a slight, nonsignificant increase at day 1, and no significant correlation was found between anterior segment changes and IOP changes.
“Higher astigmatic changes were seen in the group of 18 eyes undergoing combined phacoemulsification surgery, both at day 1 and day 7,” Carlà said. “No sutures are needed for PreserFlo implantation, and this leads to reduced postoperative astigmatism. Moreover, PreserFlo stand-alone surgery showed no significant variation in both K1 and K2.”
While glaucoma filtration surgery causes significant alterations in anterior segment parameters, PreserFlo surgery is safe, leading to minimal and only transient changes, he said.
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Carlà M, et al. Early post-operative anterior chamber parameters modifications induced by Preserflo microshunt in primary open-angle glaucoma. Presented at: European Society of Cataract and Refractive Surgeons winter meeting; March 10-12, 2023; Vilamoura, Portugal.
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