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November 16, 2023
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Percutaneous kidney biopsy seen as a safe option for small kidneys

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PHILADELPHIA — Percutaneous kidney biopsy is a feasible and safe procedure when testing patients with small kidneys, according to the results of a study presented at ASN Kidney Week.

Research into the procedure provided “an adequate sample in all cases, with an insignificant number of minor complications,” according to the study, which was headed by Ivan Zepeda Quiroz, MD, a nephrologist at the Instituto Nacional de Cardiologia Ignacio Chavez in Mexico City.

Although percutaneous kidney biopsy is a commonly used tool to diagnose chronic kidney disease and other kidney ailments, the study noted that small kidneys had been considered a contraindication for the procedure, owing to “poor accessibility and risk of complications.”

Zepeda Quiroz and colleagues performed a retrospective cross-sectional study of 25 patients. Mean age of patients was 42.3 years, and most patients were women. Mean kidney length was 7.56 cm and mean kidney width was 4.2 cm.

Researchers found that an adequate sample was received in all of the percutaneous kidney biopsies performed, with a total of five minor complications. These included three perirenal hematomas, one hematuria and one hematoma plus hematuria. Data showed that patients’ diastolic blood pressure before the procedure had the greatest association with these complications.

Histological examinations of the samples revealed a wide range of renal and glomerular conditions, including focal segmental glomerulosclerosis in 36%, lupus nephritis in 20% and crescentic glomerulonephritis in 16% of samples.

Reference:

  • Zepeda Quiroz I, et al. Feasibility and safety of percutaneous kidney biopsy in small kidneys: Breaking the paradigm. Presented at: ASN Kidney Week; Nov. 1-5, 2023; Philadelphia.