Home dialysis improves quality of life prior to dialysis dependence, many do not choose it
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ORLANDO — Patients with chronic kidney disease who choose home dialysis have improved health-related quality of life prior to dialysis dependence compared with patients on other modalities, according to a presenter at ASN Kidney Week.
However, less than half of patients in the study chose home dialysis as their treatment modality.
In a prospective study, researchers measured health-related quality of life (HRQoL) in 109 patients with advanced CKD. Patients completed the Kidney Disease Quality of Life-Short Form at baseline and every 6 months until starting dialysis. Additionally, they were given the choice to begin either home dialysis or peritoneal dialysis.
“Most of the people going home were younger, and also most of them ... were less likely to be white,” Catherine Morin, MD, co-author of the study, told Healio.
Using mixed-effect multivariable linear regression models, researchers measured physical component scores (PCS), mental component scores (MCS) and symptoms/problems of kidney disease (SPKD).
Overall, 41 patients chose home dialysis and they experienced improved HRQoL scores in the period before becoming dialysis dependent compared with patients who did not choose home dialysis. Researchers observed significantly higher PCS in patients who chose home dialysis at baseline and consistent MCS and SPKD among both groups. Researchers also noted an 8-point higher MCS among patients who chose home dialysis at each year of follow-up compared with other patients and a decrease in SPKD score over time.
“There are not a lot of people doing home dialysis, even though that’s the main thing we tried to push in our center,” Morin said. “There are a lot of unmeasured characteristics that we still have to see if they play a part in the results.”
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Morin C, et al. FR-PO513. Presented at: ASN Kidney Week; Nov. 3-6, 2022; Orlando (hybrid meeting).
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