Melanoma Video Perspectives

In a video interview, Vernon K. Sondak, MD, of Moffitt Cancer Center, discussed exciting treatment developments, cellular therapy, unmet needs in melanoma and more.

Vernon K. Sondak, MD

In a video interview, Vernon K. Sondak, MD, chair of the department of cutaneous oncology at Moffitt Cancer Center, discussed:

  • New roles of neoadjuvant therapy pre- and post-surgery;
  • Upcoming additional checkpoint inhibitors, stimulators in phase II and III clinical trials;
  • The "quiet revolution" in melanoma adaptive cellular therapy with tumor-infiltrating lymphocytes (TIL) and other immune therapies;
  • Effective, durable immune responses seen in a ‘cocktail’ of therapies, including IL-2, myelosuppressive preoperative chemotherapy;
  • The critical importance of identifying truly resistant patients and use of the TIL approach; and
  • A need to "tease out mechanisms of resistance" to provide appropriate treatments in patients.
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