Vernon K. Sondak, MD
In a video interview, Vernon K. Sondak, MD, chair of the department of cutaneous oncology at Moffitt Cancer Center, discussed:
- New roles of neoadjuvant therapy pre- and post-surgery;
- Upcoming additional checkpoint inhibitors, stimulators in phase II and III clinical trials;
- The "quiet revolution" in melanoma adaptive cellular therapy with tumor-infiltrating lymphocytes (TIL) and other immune therapies;
- Effective, durable immune responses seen in a ‘cocktail’ of therapies, including IL-2, myelosuppressive preoperative chemotherapy;
- The critical importance of identifying truly resistant patients and use of the TIL approach; and
- A need to "tease out mechanisms of resistance" to provide appropriate treatments in patients.
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