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November 18, 2024
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CDC: 1 dead in multistate outbreak of E. coli linked to organic carrots

Myeloproliferative Neoplasms News

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December 27, 2023
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VIDEO: PIM1 kinase inhibitor lowers cytokines in TP-3654 study

VIDEO: PIM1 kinase inhibitor lowers cytokines in TP-3654 study

In this video, Lindsay A.M. Rein, MD, discussed the phase 1/phase 2 TP-3654 study into relapsed/refractory myelofibrosis, data from which she presented at the ASH Annual Meeting and Exposition.

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December 24, 2023
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Ruxolitinib has positive effect on polycythemia vera symptoms

SAN DIEGO — First-line treatment with ruxolitinib led to “clinically meaningful” positive results versus best available therapy in patients with high-risk polycythemia vera, according to data presented at ASH Annual Meeting.

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November 18, 2024
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CDC: 1 dead in multistate outbreak of E. coli linked to organic carrots

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December 23, 2023
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Stem-cell treatments prolong OS for blast-phase/accelerated-phase myeloproliferative neoplasms

SAN DIEGO — Patients with Philadelphia chromosome-negative accelerated- or blast-phase myeloproliferative neoplasms who received allogeneic hematopoietic stem cells had a longer median OS than those who did not, according to a study.

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December 23, 2023
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Lower platelet count a predictor for ruxolitinib-induced thrombocytopenia

SAN DIEGO — Lower platelet count was identified as a significant predictor for ruxolitinib-induced moderate or severe thrombocytopenia in patients with myelofibrosis, according to research presented at ASH Annual Meeting and Exposition.

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December 22, 2023
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BET inhibitors combined with JAK inhibitors well-tolerated with myelofibrosis

SAN DIEGO — The BET inhibitor BMS986158 has continued to be well tolerated in combination with ruxolitinib and fedratinib in patients with intermediate- or high-risk myelofibrosis, according to a study presented at ASH Annual Meeting.

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December 22, 2023
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VIDEO: RuxoBEAT study probes ruxolitinib therapy in polycythemia vera

VIDEO: RuxoBEAT study probes ruxolitinib therapy in polycythemia vera

In this video, John Mascarenhas, MD, discussed the RuxoBEAT study into ruxolitinib treatment in patients with polycythemia vera, which was presented at the ASH Annual Meeting and Exposition.

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December 21, 2023
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VIDEO: Ruxolitinib plus navitoclax yields ‘challenging’ results in myelofibrosis

VIDEO: Ruxolitinib plus navitoclax yields ‘challenging’ results in myelofibrosis

In this video, John Mascarenhas, MD, discussed the TRANSFORM-1 study into combination therapies in myelofibrosis treatment, which was presented at the ASH Annual Meeting and Exposition.

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December 21, 2023
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VIDEO: Ruxolitinib plus pelabresib shows promise in MANIFEST-2 study

VIDEO: Ruxolitinib plus pelabresib shows promise in MANIFEST-2 study

In this video, John Mascarenhas, MD, discussed the MANIFEST-2 study into combination therapies in myelofibrosis treatment, which was presented at the ASH Annual Meeting and Exposition.

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December 20, 2023
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VIDEO: Ruxolitinib effective at treating myelofibrosis symptoms

VIDEO: Ruxolitinib effective at treating myelofibrosis symptoms

In this video, Aaron T. Gerds, MD, MS, discussed the TRANSFORM-1 and MANIFEST-2 trials into combination therapies in myelofibrosis, both of which were presented at the ASH Annual Meeting and Exposition.

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December 20, 2023
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VIDEO: TRANSFORM-1, MANIFEST-2 studies probe combo therapies in myelofibrosis

VIDEO: TRANSFORM-1, MANIFEST-2 studies probe combo therapies in myelofibrosis

In this video, Aaron T. Gerds, MD, MS, discussed the TRANSFORM-1 and MANIFEST-2 trials into combination therapies in myelofibrosis, both of which were presented at the ASH Annual Meeting and Exposition.

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