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December 20, 2023
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VIDEO: Ruxolitinib effective at treating myelofibrosis symptoms

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In this video, Aaron T. Gerds, MD, MS, discussed the TRANSFORM-1 and MANIFEST-2 trials into combination therapies in myelofibrosis, both of which were presented at the ASH Annual Meeting and Exposition.

Gerds, assistant professor of medicine at Cleveland Clinic Taussig Cancer Institute, discussed the implications of the two studies, and what effect they could have on the future of myelofibrosis study and how clinicians view treating myelofibrosis.

“It’s really time for us as a field to move past symptom improvement. What we need are drugs that deeply modify disease, eliminate aggressive clones, and prolong survival,” Gerds said.