Top gynecologic cancer stories of 2024: Genital talc powder risks; HPV vaccination
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Genital talc powder and frequent douching were associated with an increased risk for ovarian cancer, according to a recent study.
In the top story on gynecologic cancer so far in 2024, the researchers accounted for potential biases by performing a quantitative bias analysis of the potential risks of intimate care products.
“Despite challenges in assessing exposure history and biases inherent in retrospective data, our findings are robust, showing a consistent association between genital talc use and ovarian cancer,” Katie M. O’Brien, PhD, MSPH, researcher at the epidemiology branch of the National Institute of Environmental Health Sciences, said in an ASCO-issued press release. “This study leverages detailed lifetime exposure histories, and the unique design of the Sister Study, to provide more reliable evidence that supports a potential association between long-term and frequent genital talc use and ovarian cancer.”
In another top story, women vaccinated for HPV had a lower risk for cervical cancer and other HPV-related cancers compared with unvaccinated women.
Read these and more top stories on gynecologic cancer below:
1. Genital talc powder use increased risk for ovarian cancer in cohort of women, according to study results. Frequent douching and douching during young adulthood also had associations with increased ovarian cancer risk. Read more.
2. Men vaccinated for HPV less frequently developed all related cancers, particularly head and neck cancers, according to findings at ASCO Annual Meeting. The results also reaffirmed previous data that showed women vaccinated for HPV had lower risk for cervical cancer compared with women who have not received the vaccination. Read more.
3. The FDA approved pembrolizumab in combination with chemoradiotherapy for the treatment of certain women with stage III to stage IVA cervical cancer. Read more.
4. Native Hawaiian and other Pacific Islander individuals in the United States are two to three times more likely to die of certain cancers than white individuals, according to an American Cancer Society report. The report revealed this trend for what the authors characterized as “largely preventable” malignancies, such as cervical, stomach and liver cancers. Read more.
5. Cancer risk among women varied based on the type of menopausal hormone therapy they used, according to randomized study results presented at ASCO Annual Meeting. 6. Simple hysterectomy is not inferior to radical hysterectomy in terms of 3-year incidence of pelvic disease recurrence among women with low-risk cervical cancer, according to study data. Researchers also reported an association between simple hysterectomy and lower risk for urinary incontinence or retention. Read more.
7. The FDA approved the use of durvalumab (Imfinzi, AstraZeneca) in combination with carboplatin and paclitaxel followed by single-agent durvalumab for women with mismatch repair-deficient primary advanced or recurrent endometrial cancer. Read more.
8. An artificial intelligence-driven algorithm used a novel liquid biopsy assay to differentiate women with ovarian cancer from healthy patients, according to results presented at American Association for Cancer Research Annual Meeting. Read more.
Reference:
- ASCO. Study finds association between genital talc use and increased risk of ovarian cancer (press release). Available at: https://society.asco.org/about-asco/press-center/news-releases/study-finds-association-between-genital-talc-use-and-increased. Published May 15, 2024. Accessed May 16, 2024.
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