CAR T-cell Therapy Video Perspectives

Saad Usmani, MD

Usmani reports consultant/speakers bureau roles with or research finding from AbbVie, Amgen, Array Biopharma, Bristol Myers Squibb, Celgene, EdoPharma, Genentech, Gilead, GSK, Janssen Pharmaceuticals, Merck, Pharmacyclics, Oncopeptides, Sanofi, Seagen, Secura Bio, SkylineDX, Takeda and TeneoBio.
February 01, 2024
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VIDEO: CAR T-cell therapy eligibility different from transplant in multiple myeloma

Transcript

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Currently, we have FDA approval of CAR T-cell therapy in patients who’ve had four or more prior lines of treatment that include a proteasome inhibitor, an immunomodulatory drug, as well as an anti-CD38 monoclonal antibody. Right now, we have to go by the indication that is currently FDA approved. I have to say that CAR T-cell therapy eligibility is different from transplant. So we can have older, intermediate-fit patients get CAR T-cell therapies who otherwise would have not received a transplant because CAR Ts appear to have a shorter [adverse events] period, and patients recover very quickly from those side effects compared to transplantation.