CAR T-cell Therapy Video Perspectives

Nikhil C. Munshi, MD

Munshi reports serving on advisory boards or consulting for Adaptive, Abbvie, Amgen, BMS, Beigne, Janssen, Karyopharm, Legend, Novartis, Oncopep, Pfizer and Takeda; and is the scientific founder of Oncopep, Inc. and Raqia Therapeutics.
January 09, 2024
2 min watch
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VIDEO: CAR-T 'almost final step' to curing multiple myeloma

Transcript

Editor’s note: This is a previously posted video, and the below is an automatically generated transcript to be used for informational purposes. Please notify editor@healio.com if there are concerns regarding accuracy of the transcription.

CAR T-cell is almost the final step before we cure myeloma. So now we have to learn to integrate CAR T-cells into our treatment algorithm, combining it with whatever initial treatment we give and combining it with what later treatment we give. And we are beginning to develop this cure concept of how we integrate a combination therapy that, in a certain fixed period of time, not indefinite, lead to elimination of myeloma from the patient and prevent it from coming back. And so I think the area of research that we are working on is developing the best type of CAR T-cells, CAR T-cells with multifunction. We develop CAR T-cells that can be modulated so we can change the targets easily. CAR T-cells that can be combined with other agents more effectively. And the treatments following CAR T-cell, which will allow sort of mopping up of whatever myeloma cells are left so we can cure the patient. This is a very generalized statement, I'm not going into scientific detail, but in each of these area, there is significant ongoing research that brings in hope that in a very near future, we may be able to cure this disease.