VIDEO: Factor VIII variant shows ‘unclear biochemical mechanism for improved function’

BySavannah Demko

Fact checked byMindy Valcarcel, MS

In this video interview with Healio, Lindsey A. George, MD, spoke about a session on factor VIII biochemistry presented at ASH Annual Meeting and Exposition.

In the hemophilia gene therapy space, researchers presented on a factor VIII variant with “as yet unclear biochemical mechanism for improved function,” according to George, assistant professor of pediatrics at the Perelman School of Medicine at the University of Pennsylvania, and director of clinical in vivo gene therapy and attending hematologist at the Children’s Hospital of Philadelphia.

Reference:

Van Gorder L, et al. Abstract 21. Presented at: ASH Annual Meeting and Exposition; Dec. 9-12, 2023; San Diego.

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Sources/Disclosures

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Source:

Healio Interviews

Disclosures: George reports consulting for Regeneron and Spark Therapeutics; receiving research funding/royalties from AskBio; and a role on the Board of Directors or advisory committee for Regeneron. She also has a leadership/fiduciary role at STRM.BIO.

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VIDEO: Factor VIII variant shows ‘unclear biochemical mechanism for improved function’

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