Fact checked byMindy Valcarcel, MS

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August 23, 2023
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Anxiety, depression prevalent among people with hemophilia

Fact checked byMindy Valcarcel, MS
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Key takeaways:

  • Anxiety and depression are key psychiatric comorbidities for people with hemophilia.
  • Patients should undergo routine evaluation for anxiety and mood disorders.

Anxiety and depression are prevalent psychiatric comorbidities among individuals with hemophilia, according to study results.

The findings suggest clinicians should regularly evaluate these individuals for anxiety and mood disorders, researchers concluded.

image of blood cells
Anxiety and depression are prevalent psychiatric comorbidities among individuals with hemophilia. Image: Adobe Stock

Fatos D. Koseoglu, member of the faculty of medicine in the department of hematology at Izmir Bakircay University in Turkey, and colleagues conducted a cross-sectional study to assess the prevalence of anxiety and depression among adults with hemophilia A or B treated at a hemophilia center.

Investigators also evaluated correlates of these comorbidities in this population.

The analysis included 90 patients who underwent screening for anxiety and depression during annual clinic visits. The screenings included administration of the Beck Depression Inventory and State-Trait Anxiety Scale.

Three-quarters (74.4%; n = 67) of patients met criteria for significant anxiety symptoms and one-quarter (24.4%; n = 22) met criteria for significant depressive symptoms.

Multivariable analysis adjusted for confounding factors revealed no associations between depression and any clinical/psychosocial characteristics or adherence to hemophilia prophylaxis, with the exception of educational status (OR for high school education level = 1.87; 95% CI, 1.31-2.35).

Multivariable analysis showed no association between anxiety scores and clinical/psychosocial characteristics with the exception of hemophilia type (OR for hemophilia B = 1.31; 95% CI, 1.08-1.74).

“Routine evaluation for mood and anxiety disorders are crucial in the care of patients with hemophilia,” Koseoglu and colleagues concluded.