Daratumumab regimen improves outcomes in newly diagnosed multiple myeloma
NEW ORLEANS — The addition of daratumumab to lenalidomide and dexamethasone continued to benefit transplant-ineligible patients with newly diagnosed multiple myeloma, according to updated results of the randomized phase 3 MAIA study.
The daratumumab (Darzalex, Janssen) regimen appeared associated with longer PFS and OS, as well as a nearly threefold increase in minimal residual disease negativity rate, findings presented at ASH Annual Meeting and Exposition showed.
Researcher Shaji K. Kumar, MD — consultant in the division of hematology and professor of medicine at Mayo Clinic in Rochester, Minnesota — spoke with Healio about the findings and their potential implications.
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Kumar SK, et al. Abstract 4559. Presented at: ASH Annual Meeting and Exposition; Dec. 10-13, 2022; New Orleans.
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