VIDEO: Inotuzumab ozogamicin shows ‘encouraging’ results in high-risk ALL population
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Inotuzumab ozogamicin was well tolerated among patients with acute lymphoblastic leukemia who had undergone allogenic transplantation in a small study.
The phase 1 findings, presented at the ASH Annual Meeting and Exposition, showed that many patients who received inotuzumab ozogamicin (Besponsa, Pfizer) were still relapse-free at 1-year posttransplant.
These results were “very encouraging for a high-risk population,” Anjali Advani, MD, director of the inpatient leukemia program at Cleveland Clinic’s Taussig Cancer Institute, said in a video interview.
“Longer follow-up is needed, but in this population that’s high risk, you would typically expect a high risk of relapse within the first year,” Advani told Healio. “I think this will be really an exciting field to watch going forward.”
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Metheny III L, et al. Abstract 2899. Presented at: ASH Annual Meeting and Exposition; Dec. 11-14, 2021; Atlanta.
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