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May 18, 2021
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Grants fund research into link between cancer and diet, physical activity

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American Institute for Cancer Research awarded more than $1 million worth of grants to fund research designed to improve understanding of how diet, nutrition, physical activity and body weight affect cancer prevention and survivorship.

“Despite the challenges caused by the COVID-19 pandemic, [American Institute for Cancer Research (AICR)] remains dedicated to funding research that advances our understanding of how lifestyle factors impact cancer risk and outcomes,” Nigel Brockton, PhD, vice president of research for AICR, said in a press release. “People can make choices about lifestyle factors and these insights provide a valuable sense of control for people facing cancer. ... Insights from these studies will help us target cancer prevention more effectively, improve survivorship and increase public understanding of the link between lifestyle and cancer risk.”

Exercise cycle 2019
Source: Adobe Stock.

AICR has contributed more than $110 million over 3 decades to support research into the link between cancer and lifestyle.

This year’s grant recipients and their research topics are as follows:

  • Christine Brainson, PhD, of University of Kentucky Research Foundation — How dietary methionine influences lung cancer initiation and chemosensitivity;
  • Michael De Lisio, PhD, of University of Ottawa — Aberrant myelopoiesis as a novel mechanism for the differential effects of obesity and exercise on colorectal cancer risk;
  • Brian Focht, PhD, of Ohio State University — Addressing obesity to reduce cancer risk and health disparities in underserved populations;
  • Christopher Haiman, ScD, of University of Southern California — Interactions of polygenic risk score with BMI, physical activity and dietary patterns on risk for breast, colorectal and prostate cancer in a multiethnic cohort;
  • Xin Lu, PhD, of University of Notre Dame — Overcoming resistance to cancer immunotherapy with ketogenic diet-induced epigenetic reprogramming;
  • Scherezade Mama, DrPH, of The University of Texas MD Anderson Cancer Center — Feasibility of an adapted multicomponent physical activity intervention to reduce psychosocial distress among rural adults after cancer diagnosis; and
  • Erik Nelson, PhD, of University of Illinois at Urbana-Champaign — Determining the impact of different preparation techniques of foods high in cholesterol on breast cancer progression.