Prostate cancer specialist honored for translational, clinical research
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American Association for Cancer Research presented the AACR-Waun Ki Hong Award for Outstanding Achievement in Translational and Clinical Cancer Research to Nima Sharifi, MD.
The award is presented to a cancer researcher who has conducted highly meritorious translational and clinical cancer research and who is aged 50 years or younger at the time of award presentation.
Sharifi is director of Center for Genitourinary Malignancies Research at Lerner Research Institute at Cleveland Clinic; Kendrick family endowed chair for prostate cancer research at Cleveland Clinic; and professor in the department of molecular medicine at Case Comprehensive Cancer Center at Case Western Reserve University.
The award recognizes Sharifi’s contributions to the understanding of how steroid metabolism contributes to prostate cancer progression. His work helped show a gain-of-function steroidogenic enzyme missense mutation that permits dihydrotestosterone synthesis from adrenal precursors represents an effective predictive biomarker in castration-resistant prostate cancer.
“Dr. Sharifi is an outstanding physician-scientist whose discoveries have had a significant impact on our understanding of prostate cancer biology and therapeutics,” Margaret Foti, PhD, MD (hc), CEO of AACR, said in an association-issued press release. “He is renowned for his ability to make observations in fundamental biochemistry and then translate them into the clinic.”
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