Biomarker

Patients with preclinical Alzheimer’s disease had significantly greater putative retinal gliosis compared with controls, according to study results published in Investigative Ophthalmology & Visual Science.

Plasma biomarkers shed light on concussion-related neuropathology in adolescents who played contact sports in Canada, supporting their use in pathophysiology, according to new research.

Acceptance and utilization of lung cancer biomarker testing has increased in the past 6 years, but key barriers persist, according to survey results.

In this video, Barbara Blodi, MD, discusses the importance of the ellipsoid zone as a biomarker in patients with geographic atrophy.

The biomarker-based Esopredict determined that patients with Barrett’s esophagus who were stratified as higher risk were 6.4-times more likely to progress to high-grade dysplasia or esophageal adenocarcinoma within 5 years, research showed.

PHILADELPHIA — Treatment with lecanemab slowed the progression of a potential novel Alzheimer’s disease-related biomarker by 44% over 18 months compared with placebo, with the biomarker itself most correlating with tauopathy, data show.

PHILADELPHIA — In cognitively healthy but sleep-poor adults in midlife, treatment with 20 mg suvorexin led to acute decreases in Alzheimer’s-related biomarkers compared with 10 mg of the drug and placebo, according to a presenter.

Sociodemographic factors may contribute to disparities in testing for two key biomarkers among patients with metastatic colorectal cancer, according to study results.

A blood biomarker used to identify benign vs. malignant pulmonary nodules displayed “excellent” performance regardless of sex, smoking status, screen detection and nodule size, according to a research letter published in CHEST.

Emma Guttman-Yassky, MD, PhD, lives her life in dichotomy. She’s a dermatologist and an immunologist; a researcher and a department chair; and her medical and research experience transcends the globe, from North America to Europe.