Biomarker

Less than one-quarter of oncologists surveyed indicated that every one of their patients with advanced gastric or gastroesophageal junction cancers received biomarker testing consistent with practice guidelines.

A methylation biomarker panel paired with a minimally invasive sponge-capsule device identified Barrett’s esophagus, esophageal adenocarcinoma and high-grade dysplasia, according to a study published in American Journal of Gastroenterology.

The effect of levetiracetam, an antiseizure therapy, on high-frequency oscillation in patients with Alzheimer’s disease as well as epilepsy may prove its viability as a biomarker of disease pathology, according to data.

The use of dehydroepiandrosterone sulfate to determine an adrenal insufficiency diagnosis has similar accuracy to using baseline cortisol level, according to findings published in The Journal of Clinical Endocrinology & Metabolism.

Peripheral blood absolute lymphocyte count at diagnosis is an effective biomarker that can be used to risk-stratify patients with multiple myeloma, according to retrospective study results.

Presence of a protein-binding biomarker in a small cohort of adults with depression may be an indicator that suicidal ideation increases because of elevated stress, according to research from JAMA Psychiatry.

A non-invasive diagnostic model, based partially on saliva samples, distinguished between patients with and without Sjögren’s disease with high sensitivity and specificity, according to data published in Arthritis Research & Therapy.

Revised guidelines for amyloid and tau positron emission tomography for Alzheimer’s disease and dementia state these tests should only be ordered if the results will directly impact care, like when determining treatment eligibility.

Placental growth factor, a blood-based protein, may be a reliable method to detect abnormalities in the brain that presage cognitive impairment indicative of Alzheimer’s disease, data show.