Biomarker
Levetiracetam may be viable as biomarker for Alzheimer’s disease
The effect of levetiracetam, an antiseizure therapy, on high-frequency oscillation in patients with Alzheimer’s disease as well as epilepsy may prove its viability as a biomarker of disease pathology, according to data.
DHEAS may serve as biomarker for diagnosing adrenal insufficiency
The use of dehydroepiandrosterone sulfate to determine an adrenal insufficiency diagnosis has similar accuracy to using baseline cortisol level, according to findings published in The Journal of Clinical Endocrinology & Metabolism.
‘Readily available biomarker’ can predict outcomes in multiple myeloma
Peripheral blood absolute lymphocyte count at diagnosis is an effective biomarker that can be used to risk-stratify patients with multiple myeloma, according to retrospective study results.
Protein-binding biomarker may indicate stress-related increase in suicidal ideation
Presence of a protein-binding biomarker in a small cohort of adults with depression may be an indicator that suicidal ideation increases because of elevated stress, according to research from JAMA Psychiatry.
Non-invasive, saliva-based Sjögren’s diagnosis model shows good performance
A non-invasive diagnostic model, based partially on saliva samples, distinguished between patients with and without Sjögren’s disease with high sensitivity and specificity, according to data published in Arthritis Research & Therapy.
Alzheimer’s experts revise guidelines for amyloid, tau PET utilization
Revised guidelines for amyloid and tau positron emission tomography for Alzheimer’s disease and dementia state these tests should only be ordered if the results will directly impact care, like when determining treatment eligibility.
Novel blood-based biomarker may reliably detect Alzheimer’s-related brain abnormalities
Placental growth factor, a blood-based protein, may be a reliable method to detect abnormalities in the brain that presage cognitive impairment indicative of Alzheimer’s disease, data show.
Nasal spray for brain cancer, Alzheimer’s blood test: Top neurology Q&As of 2024
Healio Neurology looks back at the most popular Q&As with industry and specialty experts from the past year.
Choriocapillaris flow deficits appear lower in individuals with prediabetes
INDIANAPOLIS — While it is known that choriocapillaris flow deficits can be a biomarker for diabetes, recent data presented at Academy 2024 indicated that prediabetic patients have lower flow deficit.
Michael J. Fox Foundation awards $4.2M to support clinical trial of Parkinson’s skin test
A Phoenix-area medical technology company has received $4.2M grant fromThe Michael J. Fox Foundation for Parkinson’s Research to support a study for a skin test that quantifies abnormal alpha-synuclein in those with Parkinson’s disease.