Pediatric Endocrinology News

Children and adolescents with a high polygenic risk score for polycystic ovary syndrome tend to have a higher BMI and are more likely to develop obesity, according to study data.

Use of glucagon-like peptide 1 agonists for weight loss compared with bupropion-naltrexone was associated with an increased risk for pancreatitis, gastroparesis and bowel obstruction but not biliary disease, researchers reported in JAMA.

Incidence rates for both type 1 and type 2 diabetes diagnoses increased among children and adolescents during the COVID-19 pandemic compared with 2016 to 2019, according to study findings published in JAMA Network Open.

In a new clinical report, the AAP recommended against low- and very low-carbohydrate diets for children and adolescents with type 1 diabetes, “except under close diabetes care team supervision utilizing safety guidelines.”

State legislation prohibiting gender-confirming medical care for children and adolescents may lead to decreased access as pediatric endocrinology providers expressed concerns about their ability to practice in a survey.

Top-dose phentermine/topiramate as an adjunct to lifestyle counseling is the most cost-effective strategy for treating adolescents with obesity over 5 years, according to findings from an economic microsimulation model.

Youths with type 2 diabetes who had a lower mean HbA1c shortly after diagnosis have similar long-term beta-cell deterioration as those with a higher HbA1c, according to findings published in Diabetes Care.

Last year, the CDC updated its 22-year-old pediatric BMI-for-age growth charts to add BMIs above the 97th percentile for the first time in order to track severe obesity in children aged 2 to 19 years.

Childhood cancer survivors in France are less likely to develop obesity compared with the country’s general population, according to a study published in Obesity.

Children aged 10 to 12 years gained more weight during the COVID-19 pandemic than peers assessed before the pandemic, according to a study published in JAMA Pediatrics.