Neuroendocrinology News

A 39-year-old man presents with the complaint of erectile dysfunction, which started rather suddenly four years ago, and fatigue, which had worsened during the past year.

A 68-year-old woman with a past medical history significant for stable hypertension and hyperlipidemia managed easily with drug therapy presented with several weeks of worsening headaches and diplopia.

Patients with long-term disease control of acromegaly and deletion of exon 3 of the growth hormone receptor (d3GHR) had an increased prevalence of irreversible comorbidities such as adenomatous colonic polyps, dolichocolon and osteoarthritis.

After 15 days of treatment with pasireotide, 76% of patients with Cushing’s disease experienced a decrease in urinary free cortisol levels.

There was a high prevalence of osteoporotic vertebral fractures in men with acromegaly generally considered at low risk for osteoporosis.

Inhibin B was both a major feedback regulator of follicle-stimulating hormone and negative feedback regulator of luteinizing hormone in the follicular phase.

Later in puberty, obese girls had reduced luteinizing hormone amplitude, but elevated luteinizing hormone frequency, according to study results recently published in The Journal of Clinical Endocrinology & Metabolism.

A single 30-minute and three 10-minute bouts of physical activity increased 24-hour integrated serum growth hormone concentrations in young adults.

A 44-year-old woman was referred to the endocrine clinic with the history of pituitary macroadenoma and panhypopituitarism after a prior resection. She noted a stable visual field loss since her initial surgery and denied headache, polydipsia, polyuria, fatigue, palpations, tremor, heat/cold intolerance, diarrhea or constipation.

A 36-year-old woman was referred to the endocrine clinic with the diagnosis of severe hypothyroidism and extremely elevated TSH levels. The patient complained of persistent fatigue, amenorrhea and weight gain of 15 lb over the last two years.