Neuroendocrinology News

Adults with pheochromocytoma or paraganglioma are nearly five times more likely to experience a vertebral fracture, a hallmark of osteoporosis, when compared with adults with nonfunctional adrenal tumors, according to findings published in Bone.

A cohort of Korean women with acromegaly had a more pronounced risk for death or developing cancer during 3 years of follow-up compared with men; however, the overall incidence of acromegaly was similar to that of Western populations, according to findings from a database analysis.

Most adults with persistent or recurrent Cushing’s disease treated with the somatostatin analogue pasireotide experienced a measurable decrease in MRI-detectable pituitary tumor volume at 12 months, according to findings from a post hoc analysis of a randomized controlled trial.

Obesity is common at diagnosis of pituitary adenoma in childhood and may persist despite successful treatment, according to findings published in Clinical Endocrinology.

Approximately 20% of a cohort of adults with Cushing’s syndrome experienced at least one thrombotic event after undergoing pituitary or adrenal surgery, with the highest risk observed for those undergoing bilateral adrenalectomy, according to findings from a retrospective analysis published in the Journal of the Endocrine Society.

The national 30-day unplanned readmission rate following transsphenoidal surgery for pituitary lesion held at 10.4% between 2010 and 2015, despite a national focus on reducing readmission rates, according to findings from a database analysis published in Pituitary.

Use of the dopamine agonist cabergoline during conventional fractionated radiotherapy to treat Cushing’s disease may be associated with a higher disease recurrence rate after an initial remission, according to findings published in Clinical Endocrinology.

Children with hypogonadotropic hypogonadism or delayed puberty are more likely to develop neurodevelopment disorders, such as autism spectrum disorder, ADHD and intellectual disabilities, compared with those who undergo normal puberty, according to findings published in the Journal of Neuroendocrinology.

WASHINGTON — A class of endocrine-disrupting chemicals known as PFAS may work as an “environmental trigger” to drive multiple adverse endocrine health effects, including obesity, thyroid dysfunction and low bone mineral density, although researchers caution that more studies on potential associations are needed.

Early prenatal exposure to a mixture of endocrine-disrupting chemicals found in common consumer products is associated with lower intellectual functioning among boys at age 7 years, according to findings published in Environment International.