Bone/Mineral Metabolism News

In older Chinese men, the level of serum 25-hydroxyvitamin D was independently associated with handgrip strength, although there was no association observed for younger men or for women, according to findings from a cross-sectional study.

Preeclampsia risk is lower for women with vitamin D sufficiency in the first and third trimesters of pregnancy compared with women with vitamin D deficiency, according to findings published in Clinical Nutrition. However, vitamin D sufficiency in the first trimester alone may not be significantly associated with lower preeclampsia risk.

Adults with cerebral palsy are twice as likely to sustain a fracture of any type than the overall population, even after accounting for their higher prevalence of cardiometabolic diseases and osteoporosis, according to findings published in the Journal of Bone and Mineral Research.

Osteonecrosis of the jaw was a rare complication among older postmenopausal women with osteoporosis treated with denosumab for at least 3 years, despite 45% of women undergoing an invasive oral procedure while receiving treatment, according to findings published in The Journal of Clinical Endocrinology & Metabolism.

Children exposed to parental smoking are more likely to show evidence of impaired bone health in adulthood, including reduced bone mass, lower bone density and more low-energy fractures vs. adults not exposed to nicotine in childhood, according to findings from a longitudinal analysis.

Among older adults, hip fractures are associated with a significant, persistent negative impact on health-related quality of life over 10 years, affecting levels of mobility, self-care, ambulation and pain, according to findings published in the Journal of Bone and Mineral Research.

A report published in the Journal of Bone and Mineral Research showed little to no evidence that vertebroplasty and balloon kyphoplasty reduce pain compared with non-surgical or placebo procedures.

Women with an insufficient or deficient level of serum 25-hydroxyvitamin D are more likely to have a fasting blood glucose level of at least 100 mg/dL, indicating greater risk for type 2 diabetes, according to findings published in Menopause.

The Fracture Risk Assessment Tool, or FRAX, underestimated the observed 10-year risk for major osteoporotic fracture by up to 5% among adults with multiple sclerosis; however, calibration improved when including secondary osteoporosis or rheumatoid arthritis as proxies for additional risk, according to findings published in the Journal of Bone and Mineral Research.

Oral vitamin D doses made no impact on patients’ bone mineral density during a 12-month period in patients aged 70 years and older, according to findings recently published in American Journal of Clinical Nutrition.