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Bone/Mineral Metabolism News
Romosozumab reduces vertebral fracture risk in postmenopausal osteoporosis

Women with postmenopausal osteoporosis who received the monoclonal antibody romosozumab were less likely to sustain a vertebral fracture during 12 months of treatment compared with women who received placebo or alendronate, study data show.
Burosumab improves bone healing, quality of life in tumor-induced osteomalacia

A small cohort of adults with tumor-induced osteomalacia experienced improvements in phosphate and skeletal metabolism, physical functioning and quality of life after 144 weeks of treatment with burosumab therapy, study data show.
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Nitrogen-containing bisphosphonates reduce pneumonia risk, mortality after hip fracture

Older adults prescribed nitrogen-containing bisphosphonate therapy after a hip fracture were less likely to develop pneumonia or die from the infection compared with similar adults who received no osteoporosis therapy, researchers report.
Top endocrinology news in May: COVID-19, weight loss strategies, work hours and thyroid
In May, Healio readers were interested in sex hormones being investigated for treating COVID-19, greater COVID-19 complications for patients with diabetes and obesity, associations between thyroid dysfunction and working hours, and more.
Researchers caution against ‘misinformation’ on vitamin D during COVID-19 pandemic

There is no evidence to suggest very high doses of vitamin D can prevent or treat COVID-19, and individuals with limited access to sunlight should consider a supplement while adhering to a healthy lifestyle, researchers report.
‘Striking’ BMD increase follows surgical remission in endogenous Cushing’s syndrome

A cohort of adults with endogenous Cushing’s syndrome experienced a high rate of bone turnover immediately after surgical remission, resulting in a “striking” net increase in bone mineral density for most patients, researchers reported.
Asian ethnicity associated with atypical femur fracture risk

A cohort of Asian adults were 3.4 times more likely to experience an atypical femur fracture compared with non-Asian adults, although the incidence was still low, according to findings published in Bone.
Guideline highlights risk stratification in treating postmenopausal osteoporosis

A baseline fracture risk should guide the selection of initial osteoporosis therapy for postmenopausal women, and treatment should be continued for as long as the expected benefits outweigh the potential risks, according to an updated guideline from the American Association of Clinical Endocrinologists and the American College of Endocrinology.
BLOG: Memorial Day, minus the Indianapolis 500
For the first time since 1945, there will be no Indianapolis 500 this May. The annual event has been postponed until August, due to the COVID-19 pandemic.
Thyroid-stimulating antibody positivity may predict vertebral fracture risk in Graves’ disease

A cohort of postmenopausal Japanese women were more likely to sustain a vertebral fracture if they had thyroid-stimulating antibodies compared with women without the antibody, independent of age and severe osteoporosis status, according to findings published in Clinical Endocrinology.
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